ea0063gp135 | Obesity | ECE2019
Souza Bianca de
, Oliveira Mayara de
, Rheinheimer Jakeline
, Moehlecke Milene
, Rodrigues Michelle
, Leitao Cristiane
, Crispim Daisy
Background and aims: Obesity is a chronic multifactorial disease characterized by an excessive accumulation of body fat resulting from an imbalance between energy intake and caloric expenditure. Uncoupling protein 2 (UCP2) is located in the inner mitochondrial membrane and plays an important role in the regulation of energy expenditure. NLR family, pyrin domain-containing 3 (NLRP3) inflammasome seems to have a key role in obesity-induced inflammation through production of the ...